Michigan vs Ohio State Odds & Prediction for College Football Week 14

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Michigan vs. Ohio State at Michigan Stadium

The Ohio State-Michigan rivalry is one of the most storied in all of college football. This year's game marks the 121st meeting between the two Blue-Blood programs, and Michigan is looking to win its fifth consecutive matchup against Ohio State. Can the reigning national champions finally overcome their rivals? Below, we broke down everything that the best Ohio sportsbook has to say about this highly anticipated matchup.

Latest Michigan vs Ohio State Odds

Ohio State will travel to Ann Arbor to take on Michigan on November 29. Like always, this is the final game of the 2025-26 college football regular season. Ahead of the season, Ohio State is a 5.5-point favorite.

๐Ÿ”ข MICH vs OSU SpreadOSU -5.5
๐Ÿ“Š MICH vs OSU MoneylineOSU -198, MICH +164
๐Ÿ“ˆ MICH vs OSU Over/Under47.5
โœ… Odds Last VerifiedJuly 8, 2025

Who is Favored in Michigan vs Ohio State? 

Ohio State is currently favored by 5.5 points, according to FanDuel Sportsbook Ohio. Both teams are expected to be contenders for the CFP, but it will all come down to season performance and key player health. The Wolverines have a slight advantage with the game being in Michigan, but depending on how each team performs throughout the 2025 season, these odds will change wildly. 

Betting Promos for Michigan vs Ohio State

There are no specific betting promos currently available for the Michigan vs Ohio State game. However, bettors in Ohio can still take advantage of various welcome offers and Ohio sportsbook promos, allowing them to use bonus bets on this highly anticipated matchup. You should be able to bet the spread, moneyline, over/under, and various prop bets.

Michigan vs Ohio State Prediction

The 2025 Michigan vs Ohio State game is expected to be another intense battle between two of college footballโ€™s most historic teams. Michigan has won the last four matchups. The Wolverines have a strong foundation with core players returning and an impressive 2025 recruiting class. Michigan failed to make the CFP last season, so they will be more motivated than ever. We expect Michigan's competitive defense to come alive and put on an elite performance.

Ohio State's offense will be led by quarterback Julian Sayin, running backs James Peoples and CJ Donaldson, wide receivers Jeremiah Smith and Carnell Tate, and a solid offensive line, but even with an explosive offense, Michigan's defense will be a challenge for the Buckeyes.

OSU's defense has seen a lot of changes since last season after losing key players. But after recruiting top talent, Ohio's defense could be a threat to Michigan's new quarterback and offense. If the secondary can contain Michigan's passing attack and limit their run game, the Wolverines' offense could be shut down.

Given Ohio State's motivation to end its losing streak against Michigan and Michigan's motivation to regain itself after missing the playoffs, this will be an intense matchup with possible playoff implications. Even though sportsbooks have the Buckeyes as early favorites, we predict Michigan will get the win by a field goal.

Michigan vs Ohio State Pick: 

  • MICH: 27 | OSU: 24

When is the Michigan vs Ohio State Game?

In their annual end-of-the-year match-up, Ohio State and Michigan will play on November 29th. The Michigan vs Ohio State game is known as "The Game" and will be one of the most featured match-ups for Week 14. This game is always one of the most prominent match-ups of the college football season.

Where is Michigan vs Ohio State Being Played?

The Buckeyes will head to Ann Arbor and play at Michigan Stadium in their 121st match-up. In their history, Michigan leads the series 32-24-4 in games at Michigan Stadium. The last time Ohio State beat Michigan on the road was back in 2018.

How to Watch Michigan vs Ohio State

The Ohio State vs Michigan game kicks off at noon ET in Ann Arbor, Michigan, and will be televised on Fox. You can stream "The Game" through various services, such as Hulu + Live TV, Fubo, or any other streaming service that carries Fox.

Michigan vs. Ohio State History

Games Played:120
First Game:1897: Michigan 34 | Ohio State 0
Last Game:2024: Michigan 13 | Ohio State 10
Next Game:November 29, 2025 at Michigan Stadium in Ann Arbor, MI
All-Time Record:Michigan 62 | Ohio State 52 | Ties 6

Ohio State v Michigan Odds & Prediction FAQ

Author

Dan Thompson

Dan Thompson is a Lead Betting Analyst for BetOhio.com. Dan's unique experience makes him the perfect fit to find the latest storylines and interesting betting angles impacting Ohio sports betting.

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